Centro3R | Centro Interuniversitario per la Promozione dei Principi delle 3R nella Didattica e nella Ricerca

Centro Interuniversitario per la Promozione dei Principi delle 3R nella Didattica e nella Ricerca

REFINEMENT

improving experimental design and methods to alleviate or minimise pain, suffering or distress in animals

REPLACEMENT

substitution of procedures on animals with alternative methods of equivalent or better validity and translational value

REDUCTION

reducing the number of animal used in scientific procedures

Publications

Biomedical Research on Substances of Abuse: The Italian Case Study

Language Undefined

Le sostanza d'abuso possono causare dipendenza e alterazione della coscienza.

DOI:

10.1177/02611929221132215

Biomimetic design of bioartificial scaffolds for the in vitro modelling of human cardiac fibrosis

Language EN

2D and 3D models of early-stage postinfarct fibrotic tissue were engineered on bioartificial scaffolds with biomimetic composition, design, and surface stiffness.

DOI:

10.3389/fbioe.2022.983872

An In Vitro Engineered Osteochondral Model as Tool to Study Osteoarthritis Environment.

Language Undefined

L'osteoartrosi (OA) è una patologia degenerativa articolare caratterizzata da danni meccanici e infiammatori a carico della sinovia, della cartilagine articolare (AC) e dell'osso subcondrale (SB).

DOI:

https://doi.org/10.1002/adhm.202202030

Hydrogels as Corneal Stroma Substitutes for In Vitro Evaluation of Drug Ocular Permeation

Language Undefined

Hydrogels are complex hydrophilic structures, consisting of crosslinked homopolymers or copolymers insoluble in

DOI:

doi: 10.3390/pharmaceutics14040850

The Rise of Three Rs Centres and Platforms in Europe

Language Undefined

Public awareness and discussion about animal experiments and replacement methods has greatly increased in recent years.

DOI:

https://journals.sagepub.com/doi/10.1177/02611929221099165

News

26 September 2022

Publications

Biomedical Research on Substances of Abuse: The Italian Case Study

Biomimetic design of bioartificial scaffolds for the in vitro modelling of human cardiac fibrosis

An In Vitro Engineered Osteochondral Model as Tool to Study Osteoarthritis Environment.

Hydrogels as Corneal Stroma Substitutes for In Vitro Evaluation of Drug Ocular Permeation

The Rise of Three Rs Centres and Platforms in Europe

News

Il centro 3R a EUSAAT!

SCHEER - Call for external experts for the SCHEER WG on the protection of animals used for scientific purposes

Bioprinting Winter School

3days for 3Rs

Finanziamenti dal Ministero della Salute per UNIPI e UNIGE

Immunotherapy for Infectious Diseases Conference-June 20-23, 2022 AULA MAGNA, University of Pavia - Italy